关于骨关节炎重要的姜黄素：替代NSAID降低风险
How does curcumin, the Turmeric extract, help in Osteoarthritis?
Curcumin is a naturally occurring compound found in the turmeric spice and has been studied for its potential health benefits.
Due to its anti-inflammatory and antioxidant effects, curcumin may have promising implications for managing osteoarthritis. In fact, studies have suggested that curcumin could help reduce pain and improve joint function in individuals with this condition.
Curcumin, a natural compound found in turmeric, may help with osteoarthritis in the following ways:
- Reducing joint inflammation: Osteoarthritis causes joint inflammation, which can lead to pain and swelling. Curcumin has anti-inflammatory properties that may help to reduce these symptoms.
- Protecting cartilage: Cartilage is a tissue that cushions the joints and allows them to move smoothly. In osteoarthritis, enzymes can break down cartilage and cause joint damage. Curcumin has been shown to block these enzymes, which may slow down the progression of osteoarthritis.
- Providing antioxidant effects: Curcumin is also an antioxidant, which means it can neutralize harmful molecules that can damage cells and tissues in the joints, causing inflammation and pain.
- Modulating the immune system: Curcumin can affect cytokines and inflammatory cells in the immune system. In osteoarthritis, it may help to reduce pro-inflammatory cytokines that contribute to joint damage. While curcumin has shown promise in reducing pain and improving joint function in people with osteoarthritis, more research is needed to fully understand its benefits and how it can be used as part of an osteoarthritis treatment plan. Additionally, curcumin has low bioavailability, so it may be necessary to take it in combination with other compounds to enhance its absorption. As with any supplement or treatment, it is important to talk to a pharmacist before taking curcumin.
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What are the outward and visible symptoms of Osteoarthritis which curcumin from Turmeric are helping to reduce?
Osteoarthritis is known to limit movements, causing pain and creating inflexibility at the affected joints and surrounding areas. In order to reduce these symptoms, we can use Curcumin, an extract from Turmeric.
How to take curcumin?
By taking 500mg to 750mg of curcumin orally twice a day with meals, patients can potentially reduce the immobility, pain, and stiffness associated with Osteoarthritis.
It’s important to note that better absorption of curcumin can be achieved by consuming it with meals.
How long does it take to see effect?
One thing to bear in mind, though, is that we need to take curcumin for days if not weeks to get the therapeutic results.
And, on the other hand, Medicines such as steroids and Non-steroidal anti-inflammatory drugs (NSAIDs), for example, Ibuprofen, Naproxen Sodium, and Diclofenac, can quickly reduce the symptoms of osteoarthritis. They can take effect in just a few hours, unlike other treatments.
Nevertheless, prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs) or steroids may result into many serious side effects; hence, there is a need to develop herbal medicines, having good pain-killing agent without side effects. And these herbal medicines include the curcumin and/or its relatives.
List of Clinical Trials of Turmeric Curcumin on Osteoarthritis
- Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study
- Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study
- Efficacy as well as safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients
- Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study
- Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study
- Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study
- Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis
- A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA
- Curcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled trial
- Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis
- The efficacy of Curcuma Longa L. extract as an adjuvant therapy in primary knee osteoarthritis: a randomized control trial
- Curcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trial
- Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial
Medical Disclaimer Reminder:
As a disclaimer, it’s important to note that the information presented here about “Important Curcumin from Turmeric for Osteoarthritis to kill NSAID harms” is intended solely for informational purposes. It should not be construed as medical or health advice for any particular condition. Therefore, it is strongly recommended that readers consult licensed health professionals before taking any action based on the information provided here.
This is because, as the saying goes, “no one knows what they don’t know,” and seeking professional advice can help ensure that important information is not overlooked. Trained and registered professionals, such as pharmacists, nutritionists, dietitians, and others, are available to provide guidance and support.
Additionally, it’s important to keep in mind that the information presented here is subject to change as new data becomes available. Therefore, it’s essential to stay up-to-date on the latest developments and recommendations related to this topic and related issues.